Mineral dissolution is central to weathering, reactive flow and transport, ore processing, and more. Interpreting observed rates in terms of a molecular scale dissolution mechanism often requires ...
The aim of this study was to probe the dissolution mechanisms of amorphous solid dispersions (ASDs) of a poorly water-soluble drug formulated with a hydrophilic polymer. Ritonavir (RTV) and ...
Fractures play an important role as flow paths in porous media. When an undersaturated reactive fluid is flowing in a fracture, the dissolution process will alter the flow paths locally. Dissolution ...
This project aims to investigate the release performance of bilayer tablet (BL-Tablet) designed with both fast and slow-release technology, targeting sleep disorders. The tablet incorporates Melatonin ...
Dissolution studies were carried out under nonsink conditions, and solution phase behavior was characterized using several orthogonal techniques. It was found that liquid–liquid phase separation (LLPS ...
The aim of this work is to develop and validate a dissolution test for glibenclamide tablets. Optimal conditions to carry out the dissolution test are 500 mL of phosphate buffer at pH 8.0, paddles at ...